Antineoplastic effects of mammalian target of rapamycine inhibitors
نویسندگان
چکیده
منابع مشابه
The Role of Mammalian Target of Rapamycine Signaling Pathway in Central Nervous System Cancers: A Review
Mammalian mechanistic target of rapamycine (mTOR) is a conserved serine/threonine kinase in the cellular PI3K/Akt/mTOR signaling pathway. This pathway is modified by cellular alterations such as level of energy, growth factors, stresses, as well as the increased environmental level of cancerous cytokines. In general, increase of this kinase protein function is seen in various types of cancers, ...
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ژورنال
عنوان ژورنال: World Journal of Transplantation
سال: 2012
ISSN: 2220-3230
DOI: 10.5500/wjt.v2.i5.74